GRAS Reference 2539

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Updated use levels and food categories collected as part of the FDA’s SLR project are available from the FEMA office for this flavor ingredient upon request.

Most Recent NUL/FC Published

FEMA GRAS Categories and Use Levels are available in the categories as listed in the above publication with an update to the Chewing Gum category in GRAS 25.

Safety Assessment

Adams T.B., Greer D.B., Doull J., Munro I.C., Newberne P.M., Portoghese P.S., Smith R.L., Wagner B.M., Weil C.S., Woods L.A. and Ford R.A. 1998. The FEMA GRAS assessment of lactones used as flavor ingredients. Food and Chemical Toxicology. 36, 249.

Quick Reference

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FEMA Number
2539
JECFA Number
225
CAS
105-21-5
CFR
21CFR172.515

JECFA Summary 225

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Safety evaluation of certain food additives and contaminants prepared by the forty-ninth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA). WHO Food Additives Series No. 40, 1998.

SLR

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SLR B1C. Scientific literature review of aliphatic lactones. PB86155850. National Technical Information Service. 1985.